ANFOTERICINA B LIPOSOMAL PDF

More What is amphotericin B liposomal? Amphotericin B liposomal is an antifungal medicine that is used to treat serious, life-threatening fungal infections including leishmaniasis, or a certain form of meningitis in people infected with HIV human immunodeficiency virus. Amphotericin B liposomal is not for treating a minor fungal infection such as a yeast infection of the mouth, esophagus, or vagina. Amphotericin B liposomal may also be used for purposes not listed in this medication guide.

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More What is amphotericin B liposomal? Amphotericin B liposomal is an antifungal medicine that is used to treat serious, life-threatening fungal infections including leishmaniasis, or a certain form of meningitis in people infected with HIV human immunodeficiency virus.

Amphotericin B liposomal is not for treating a minor fungal infection such as a yeast infection of the mouth, esophagus, or vagina. Amphotericin B liposomal may also be used for purposes not listed in this medication guide. Important Information Tell your caregivers if you feel dizzy, nauseated, light-headed, sweaty, hot or cold, or if you have a fast heartbeat , chest tightness, or trouble breathing while you are receiving amphotericin B liposomal.

Before taking this medicine You should not be treated with amphotericin B if you are allergic to it. Tell your doctor if you have ever had: kidney disease; liver disease ; or an electrolyte imbalance such as high or low levels of potassium or magnesium in your blood. Tell your doctor if you are pregnant. It is not known whether amphotericin B liposomal will harm an unborn baby. You should not breast-feed while using amphotericin B liposomal.

How is amphotericin B liposomal given? Amphotericin B liposomal is given as an infusion into a vein. A healthcare provider will give you this injection.

Amphotericin B liposomal may need to be given for up several weeks or months, depending on the infection being treated. Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely.

What happens if I miss a dose? If amphotericin B liposomal is given while you are in the hospital, you are not likely to miss a dose. If you are receiving this medicine in an outpatient clinic, call your doctor for instructions if you miss an appointment for your amphotericin B liposomal injection.

What happens if I overdose? Since amphotericin B liposomal is given by a healthcare professional in a medical setting, an overdose is unlikely to occur. What should I avoid while receiving amphotericin B liposomal? Amphotericin B liposomal side effects Get emergency medical help if you have signs of an allergic reaction: hives ; difficult breathing; swelling of your face, lips, tongue, or throat. Some side effects may occur during the injection.

Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, hot or cold, or if you have a fast heartbeat, chest tightness, or trouble breathing. Call your doctor at once if you have: kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; low calcium level--muscle spasms or contractions, numbness or tingly feeling around your mouth, or in your fingers and toes ; low magnesium-- dizziness , irregular heartbeats, feeling jittery, muscle cramps, muscle spasms, cough or choking feeling; or low potassium level--leg cramps, constipation , irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.

Common side effects may include:.

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Amphotericin B

Shaktijin There was a problem providing the content you requested However, some morphological changes on apical cytoplasm like lots number of lysosomes, lytic areas and vacuolar structures in tubuler epithelium in rat kidneys have been shown after in h use of Abelcet Figs. The animals were divided into 6 groups each including six rats: Country Reference Study design No. Ann Intern Med ; Pharmacokinetics and safety of a unilamellar liposomal formulation of amphotericin B AmBisome in rabbits. Risk factors for kala-azar in Bangladesh. Cytoplasmic protrusion arrowdeep basal folding asterix are striking. Most of the data available are from case series[ 41 — 43 ] [ Table 2 ]. Singledose liposomal amphotericin B in the treatment of visceral leishmaniasis in India: Results of the national surveillance program for the years Multicenter randomized trial of fluconazole versus amphotericin B for treatment of candidemia in non-neutropenic patients.

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Amphotericin B liposomal

Intravenous[ edit ] Amphotericin B alone is insoluble in normal saline at a pH of 7. Therefore, several formulations have been devised to improve its intravenous bioavailability. It was approved by the FDA in Fungisome [24] is a generic liposomal complex of amphotericin B marketed by Lifecare Innovations of India. Lipid complex formulations[ edit ] A number of lipid complex preparations are also available. Abelcet was approved by the FDA in Two molecules of each form a tetramer that aggregate into spiral arms on a disk-like complex.

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Amphotericin B (Liposomal)

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ANFOTERICINA B LIPOSOMAL PDF

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